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A section of the TIC (14.6 to 18.3 minute) is expanded, as shown in the middle portion of Figure 2.

The top portion of the figure is the total ion chromatogram (TIC) of the extract. The term deconvolution is used here in the broad sense of extracting signals from a complex mixture, as depicted in Figure 1.ĭeconvolution is the goal of AMDIS (Automatic Mass Spectral Deconvolution and Identification Software) developed by NIST (National Institute of Standards and Technology) for detecting chemicals in violation of Chemical Weapons Convention.įigure 2 is an example of using AMDIS to identify trace levels of one of the target compounds, methyl parathion, in grape extract. Two powerful GC/MS techniques-Retention Time Locking (RTL) and peak deconvolution-have been combined to create a quantitation and screening tool that can identify 567 pesticides and endocrine disrupters from a single run in a minute or two.Įasily find target compounds in complex matrices This is a time-consuming process it can take an experienced analyst an hour to review/confirm one data file. Background subtraction and manual integration are often required to be certain of the results. It is always very difficult to identify target compounds from a high matrix background because the matrix affects the ion ratios of the target compounds. Typical target compound analysis requires finding target ions and meeting qualifier ion ratios. New software eliminates manual data processingīy Chin-Kai Meng, Ph.D., and Mike Szelewski This finally fixed the problem! When Chemstation was restarted, the data folder was fully expanded showing all existing subfolders.Agilent Newsletter - Find Hidden Target Compounds These two files did not seem to be associated (by name) to any other subfolder so I removed them. I then happened to notice that there were a couple single files (*.B and *.S) directly within the parent data folder. I checked the size of the folder and it appeared like it had recently surpassed 2.0 GB, so I removed a few subfolders in case that was a limit.

The new data folder could not be expanded in the Data Analysis view.

I happily copied ALL the files in the old folder to the new folder, but then the problem came back. I updated the path configuration and started up Chemstation and the folder showed correctly (yeah!). B.03.02(341) on WinXP SP3) and your posting led us eventually to a different solution.Īt first, I created another data folder as you instructed and transferred a few data files into it.